Colleen Woods, MS, RDN, CLC

Feb 125 min

Can strawberries build immunity?

Strawberries are nutritional powerhouses.

Can strawberries support your immune system?

Evidence from clinical studies suggest they can.

Since the pandemic, the surge of flu, and the surfacing of RSV, misleading claims are being made regarding products that can keep the immune system not only healthy, but also prevent people from contracting viruses.

Factors that can influence immunity include non-genetic behaviors and bacteria[i]:

  • Diet

  • Sleep

  • Stress

  • Exercise

  • Microbiome

  • Germs

How Does Diet Factor into Immunity?

Whole foods can promote overall health. While there is no single food that will boost the immune system to the point of preventing any disease, eating a balanced diet will help maintain a strong immune system.

The Dietary Guidelines for Americans promotes the “My Plate” method of balancing the diet:

My Plate recommends making half your plate fruits and vegetables.

  • Colorful fruits and non-starchy vegetables make up ½ the plate

  • Lean protein makes up one-quarter of the plate

  • Whole grains or starch make up the last quarter of the plate

  • Low-fat dairy is optional at each meal for those who tolerate lactose[ii].

Will Strawberries Boost My Immune System?

Because of strawberries’ high vitamin C content, consumers are considering purchasing them alongside the well-known vitamin-C powerhouse the "orange." But can strawberries build immunity? Healthcare professionals support this dietary addition even though no foods can actually "boost" immunity.

Some question if vitamin C supplements aren’t proven to enhance immunity, why would health professionals support eating more strawberries?

To begin with, vitamin C from fruit and veggies is the best source of vitamin C- not supplements.[iii] Food sources of vitamin C are more effective at supporting the immune system and overall health than supplements.

In addition, strawberries offer much more than vitamin C; all of their micronutrients work together synergistically to help prevent and fight disease.

Strawberries have powerful antioxidants, polyphenols, vitamin C, and more to build immune system responses.

Based on clinical evidence, here are the facts about strawberries’ immune-building properties:

  • Young and older people with underlying chronic conditions including heart disease, high blood pressure, cancer, respiratory dysfunction, and diabetes are at higher risk for contracting COVID-19, flu, and RSV.[iv] Strawberries have been shown to fight against many chronic diseases by helping to lower LDL cholesterol [v],[vi], carcinogenic activity[vii], blood sugars and insulin resistance [viii],[v] and improving artery function.[ix]

  • Strawberries may increase the immunological response of the immunity cells T-lymphocytes and monocytes in obese people who are at greater risk for developing infections.[x]

  • The red berries help support cell survival, growth, and antioxidant defense. [iii]

  • Strawberries protect and repair DNA damage. [iii]

  • A serving of eight strawberries has a full day’s worth of vitamin C. [xii]

  • Strawberries display antimicrobial action. [v]

  • Strawberries act as a prebiotic and can positively alter the gut microbiome when eaten daily. [v] Strawberries are also a low FODMAP food, making them good for the guts of people with IBS, SIBO, and other GI issues.

  • In a study of healthy adults, eating strawberries for short- and medium-term led to significant increases in antioxidants, folate, and vitamin C in the body as well as to significant improvements of white blood cell resistance to external stress.[xiii]

Do Supplements Help the Immune System?

Outside of supplementing with vitamin D if you’re deficient in the vitamin (many are in the winter who live in northern climates), there is no clinical evidence that supplements are effective in bolstering the immune system, despite the many dubious claims being made on social media, TV ads, and the internet.

There is little evidence that popping extra zinc lozenges, vitamin C tablets, elderberry or echinacea can help. In fact, a person can cause harm by overloading on certain vitamins (like vitamin C and zinc), minerals, and any supplements not prescribed by a doctor [ii].

There's little evidence to support supplements' ability to boost immunity. They can even cause harm.

What Can I Do to Build My Immunity?

The best actions you can take to build your immune system up refers back to the list of behaviors at the top of this article.

Diet

Eat a well-balanced diet with the rainbow of fruits and vegetables each week to increase antioxidant, vitamin, and mineral stores. Eight strawberries are equivalent to 1 serving of fruit, and a full day’s worth of vitamin C.

Protein is also essential for growth and illness recovery. If choosing a vegetarian protein source, eating vitamin C-rich foods with plant protein increases absorption of iron that is otherwise low in bioavailability.

Sleep

Do your best to get adequate sleep each night (7-8 hours each night).

Stress

While stress is a part of life, techniques to help manage it may include talking to someone, checking in on loved ones, exercise, sleep, and eating a nutritious diet.

Microbiome & Germs

We can’t neglect the role our bacteria play in health. It’s critical to feed the gut good bacteria via pre- and pro-biotic foods like yogurt, fruits, vegetables, and fermented foods.

Heed advice of health authorities. The CDC website is a reliable source of information on viruses and other infectious diseases.

Virtual nutrition appointments are available with a Registered Dietitian here.

References

  1. [i] Brodin, P., Jojic, V., Gao, T., Bhattacharya, S., Angel, C. J., Furman, D., Shen-Orr, S., Dekker, C. L., Swan, G. E., Butte, A. J., Maecker, H. T., & Davis, M. M. (2015). Variation in the human immune system is largely driven by non-heritable influences. Cell, 160(1-2), 37–47. https://doi.org/10.1016/j.cell.2014.12.020
     
    [ii]United States Department of Agriculture. (2020). What is my plate? ChooseMyPlate.gov. https://www.choosemyplate.gov/eathealthy/WhatIsMyPlate
     
    [iii]Office of Dietary Supplements. (2020). Vitamin C. National Institutes of Health. https://ods.od.nih.gov/factsheets/VitaminC-Consumer/
     
    [iv]Rabin, R.C. (March 12, 2020). Coronavirus is an even worse threat to more than half of Americans. New York Times. https://www.nytimes.com/2020/03/12/health/coronavirus-midlife-conditions.html
     
    [v]Djurica, D., Holt, R., Ren, J., Shindel, A., Hackman, R., & Keen, C. (2016). Effects of a dietary strawberry powder on parameters of vascular health in adolescent males. British Journal of Nutrition, 116(4), 639-647. doi:10.1017/S0007114516002348
     
    [vi]Burton-Freeman, B., Linares, A., Hyson, D., & Kappagoda T. (2010). Strawberry modulates LDL oxidation and postprandial lipemia in response to high-fat meal in overweight hyperlipidemic men and women. Journal of the American College of Nutrition, 29(1):46-54. 10.1080/07315724.2010.10719816
     
    [vii]Zhang Y, Seeram NP, Lee R, Feng L, Heber D. (2008). Isolation and identification of strawberry phenolics with antioxidant and human cancer cell antiproliferative properties. Journal of Agriculture & Food Chemistry, 56(3), 670-675.
     
    [viii] Eunyoung, P., Edirisinghe, I., Wei, H., Prabha, L., Katarzyna, V., et al. (2016). A dose–response evaluation of freeze‐dried strawberries independent of fiber content on metabolic indices in abdominally obese individuals with insulin resistance in a randomized, single‐blinded, diet‐controlled crossover trial. Molecular Nutrition & Food Research, 60(5), 1099-1109. https://doi.org/10.1002/mnfr.201500845
     
    [ix]Tulio, Jr. A.Z., Chang, C., Edirisinghe, I., White, K.D., Jablonski JE, et al. (2012). Berry fruits modulated endothelial cell migration and angiogenesis via phosphoinositide-3 kinase/protein kinase B pathway in vitro in endothelial cells. Journal of Agriculture & Food Chemistry, 60(23), 5803-12. doi: 10.1021/jf3001636.
     
    [x]Zunino, S., Storms, D., Freytag, T., Mackey, B., Zhao, L., Gouffon, J., & Hwang, D. (2013). Dietary strawberries increase the proliferative response of CD3/CD28-activated CD8 T cells and the production of TNF-α in lipopolysaccharide-stimulated monocytes from obese human subjects. British Journal of Nutrition, 110(11), 2011-2019. doi:10.1017/S0007114513000937
     
    [xi]Giampieri, F., Forbes-Hernandez, T.Y., Gasparrini, M., Alvarez-Suarez, J.M., Afrin, S., et al. (2015). Strawberry as a health promoter: An evidence based review. Food & Function, 6, 1386-1398. https://doi.org/10.1039/C5FO00147A
     
    [xii]USDA. (2020). National Nutrient Database for Standard Reference (version 1.2.2, release 25) [computer software].
     
    [xiii]Battino, M., Forbes-Hernandez, T.Y., Gasparrini, M., Afrin, S., Mezzetti, B. and Giampieri, F. (2017). The effects of strawberry bioactive compounds on human health. Acta Hortic. 1156, 355-362. https://doi.org/10.17660/ActaHortic.2017.1156.54

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